Koji Nakayama

Organization・Title
Professor, Infection Research, Graduate School of Biomedical Sciences
Special field
Morphological Basic Odontology (Microbiology)
Research themes
Molecular genetical approach to study the periodontopathogenesis of Porphyromonas gingivalis

You must learn the basic knowledge of bacteria to understand infectious diseases caused by bacteria.

personal history

1977.3 Kyushu University, Faculty of Dentistry, Graduated
1981.3 Kyushu University, Graduate School, Division of Dental Research, Doctor Course, Accomplised credits for doctoral program
1981.4 - 1991.3 Kyushu University School of Dentistry, Research Associate
1986.9 - 1988.8 Washington University at St. Louis, Visiting Researcher
1991.4 - 2000.3 Kyushu University School of Dentistry, Associate Professor
2000.4 - 2000.11 Kyushu University Graduate School of Dental Science, Associate Professor
2000.12 - 2002.3 Nagasaki University, School of Dentistry, Professor
2002.4 - Nagasaki University, Graduate School of Biomedical Sciences, Graduate School of Biomedical Science, Professor
2005.10 - 2007.9 Nagasaki University, School of Dentistry, Vice Dean
2005.10 - 2006.3 Nagasaki University, Graduate School of Biomedical Sciences, Vice Dean of Graduate School of Biomedical Sciences
2006.4 - 2008.10 Nagasaki University, Headquarters for Planning and Evaluation, Presidential Aide

works/thesis

1. Sato K, Naito M, Yukitake H, Hirakawa H, Shoji M, McBride MJ, Rhodes RG, and Nakayama K:A protein secretion system linked to bacteroidete gliding motility and pathogenesis. Proc. Natl. Acad. Sci. USA,107:276-281,2010.

2. Naito M, Hirakawa H, Yamashita A, Ohara N, Shoji M, Yukitake H, Nakayama K, Toh H, Yoshimura F, Kuhara S, Hattori M, Hayashi T, and Nakayama K:Determination of the genome sequence of Porphyromonas gingivalis strain ATCC 33277 and genomic comparison with strain W83 revealed extensive genome rearrangements in P. gingivalis. DNA Research,15(4):215-225, 2008.

3. Sakai E, Naito M, Sato K, Hotokezaka H, Kadowaki T, Kamaguchi A, Yamamoto K, Okamoto K, Nakayama K:Construction of recombinant hemagglutinin derived from the gingipain-encoding gene of Porphyromonas gingivalis, identification of its target protein on erythrocytes, and inhibition of hemagglutination by an interdomain regional peptide, J Bacteriology,189(11):3977-3986,2007.

4. Fujimura Y, Hotokezaka H, Ohara N, Naito M, Sakai E, Yoshimura M, Narita Y, Kitaura H, Yoshida N, and Nakayama K.:Hemoglobin receptor protein (HbR) of Porphyromonas gingivalis inhibits receptor activator NF-kappaB ligand-induced osteoclastogenesis from bone marrow macrophages. Infection and Immunity,74(5):2544-2551, 2006.

5. Naito M, Sakai E, Shi Y, Ideguchi H, Shoji M, Ohara N, Yamamoto K, and Nakayama K.:Porphyromonas gingivalis-induced platelet aggregation in plasma depends on Hgp44 adhesin but not Rgp proteinase. Molecular Microbiology,59(1):152-167, 2006.